SCHEMBL11770352

SCHEMBL11770352

O=P(O)(Cl)c1ccccc1-c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.43
ALDH1A1 P00352 2/20 0.41
HSD17B10 Q99714 2/20 0.41
HPGD P15428 1/20 0.41
BCL2L1 Q07817 1/20 0.41
CYP2A6 P11509 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
BCAT2 O15382 1/20 0.39
CHRNB2 P17787 1/20 0.39
CHRNB4 P30926 1/20 0.39
CHRNA3 P32297 1/20 0.39
CHRNA4 P43681 1/20 0.39
ACP3 P15309 2/20 0.38
BACE1 P56817 1/20 0.38
CA2 P00918 1/20 0.38
CA4 P22748 1/20 0.38
CA5A P35218 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL563975 0.83 POLB (0.47) GPR84ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL1965079 0.83 ALDH1A1 (0.44) GPR84ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL14244855 0.83 CYP2A6 (0.44) GPR84ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL6003033 0.83 CYP2A6 (0.44) GPR84ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL1256220 0.79 GPR84 (0.43) GPR84ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL30729584 0.79 ACP3 (0.47) GPR84ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL28495219 0.79 BCAT2 (0.44) GPR84ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL11144673 0.78 ALDH1A1 (0.42) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL29822328 0.78 CA2 (0.46) GPR84ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL3646058 0.78 CA2 (0.46) GPR84ALDH1A1HSD17B10HPGDBCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3980644-A EXTRACTION WITH CYCLOHEXANONE ELI LILLY AND COMPANY (US) 1976-09-14 US disclosed