Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MDH2 | P40926 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11771511 | 0.81 | POLB (0.67) | DRD2DRD3ALDH1A1MEN1KMT2A | |
| SCHEMBL11735457 | 0.79 | GABRA1 (0.47) | ALDH1A1HPGDMDH2SMN1; SMN2LTA4H | |
| SCHEMBL11602121 | 0.78 | ALDH1A1 (0.61) | ALDH1A1HPGDMDH2SMN1; SMN2LTA4H | |
| SCHEMBL11768689 | 0.77 | DRD3 (0.58) | DRD2DRD3LTA4HPLA2G2APOLB | |
| SCHEMBL7947691 | 0.77 | ALDH1A1 (0.62) | ALDH1A1HPGDMDH2SMN1; SMN2KMT2A | |
| SCHEMBL7945905 | 0.77 | ALDH1A1 (0.58) | ALDH1A1HPGDMDH2SMN1; SMN2GABRA1 | |
| Hydrochloric Acid SCHEMBL11767138 | 0.77 | LTA4H (0.59) | DRD2DRD3LTA4HPLA2G2APOLB | |
| SCHEMBL11194622 | 0.77 | ALDH1A1 (0.59) | ALDH1A1HPGDMDH2SMN1; SMN2LTA4H | |
| SCHEMBL7382353 | 0.75 | MEN1 (0.64) | ALDH1A1HPGDMDH2SMN1; SMN2LTA4H | |
| SCHEMBL6098744 | 0.75 | ALDH1A1 (0.57) | ALDH1A1HPGDMDH2SMN1; SMN2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE28973-E | PARKINSON'S DISEASE | A. H. ROBINS COMPANY, INCORPORATED (US) | 1976-09-21 | — | — | US | disclosed |