Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 5/20 | 0.58 |
| ▸ | DRD2 | P14416 | 4/20 | 0.58 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | LTA4H | P09960 | 2/20 | 0.57 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.57 |
| ▸ | HTR1D | P28221 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11767138 | 0.99 | LTA4H (0.59) | DRD3DRD2TRPM8KDM4EMAPT | |
| SCHEMBL32669329 | 0.86 | TRPM8 (0.67) | TRPM8KDM4EMAPTLTA4HPLA2G2A | |
| SCHEMBL11769854 | 0.85 | HTR7 (0.67) | DRD3DRD2MAPTSLC6A4DRD4 | |
| SCHEMBL11254792 | 0.81 | DRD3 (0.72) | DRD3DRD2MAPTSLC6A4DRD4 | |
| SCHEMBL6968414 | 0.78 | DRD3 (0.56) | DRD3DRD2HTR1DSLC6A4DRD4 | |
| SCHEMBL8186456 | 0.78 | HRH3 (0.65) | DRD3DRD2KDM4ELTA4HPOLB | |
| SCHEMBL11776900 | 0.77 | DRD2 (0.50) | DRD3DRD2TRPM8KDM4EMAPT | |
| SCHEMBL11738116 | 0.77 | HTR6 (0.56) | TRPM8KDM4EMAPTLTA4HPLA2G2A | |
| SCHEMBL6388022 | 0.77 | POLB (0.78) | TRPM8KDM4EMAPTLTA4HPLA2G2A | |
| SCHEMBL11471775 | 0.75 | TRPM8 (0.53) | TRPM8KDM4EMAPTLTA4HPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE28973-E | PARKINSON'S DISEASE | A. H. ROBINS COMPANY, INCORPORATED (US) | 1976-09-21 | — | — | US | disclosed |