Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11776597 | 0.88 | CTSL (0.50) | KMT2AMEN1MAPTALDH1A1TPH1 | |
| SCHEMBL11773935 | 0.84 | RAB9A (0.49) | SMN1; SMN2MAPTKDM4EALDH1A1GAA | |
| SCHEMBL11744597 | 0.74 | CA2 (0.63) | PRSS1PRSS2PRSS3CTSLPPARG | |
| SCHEMBL11781869 | 0.73 | CTSL (0.48) | KMT2AMEN1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL16180672 | 0.72 | PRSS1 (0.64) | KMT2AMEN1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL9683516 | 0.71 | KMT2A (0.69) | KMT2AMEN1SMN1; SMN2MAPTPRSS1 | |
| SCHEMBL28003430 | 0.71 | KMT2A (0.69) | KMT2AMEN1SMN1; SMN2MAPTPRSS1 | |
| SCHEMBL10599787 | 0.71 | KMT2A (0.69) | KMT2AMEN1SMN1; SMN2MAPTPRSS1 | |
| SCHEMBL610755 | 0.71 | KMT2A (0.69) | KMT2AMEN1SMN1; SMN2MAPTPRSS1 | |
| Hydrochloric Acid SCHEMBL7427975 | 0.70 | PRSS1 (0.62) | KMT2AMEN1SMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4004008-A | ANTISPASMODIC, VASODILATION | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1977-01-18 | — | — | US | disclosed |