Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 7/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CDC42 | P60953 | 1/20 | 0.46 |
| ▸ | RAC1 | P63000 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10537588 | 0.86 | TRPM8 (0.49) | TSHRLMNAMAPTNPC1TP53 | |
| SCHEMBL11782640 | 0.81 | AKR1C3 (0.46) | ABCB11AKR1C3AKR1C2PTGS1PTGS2 | |
| SCHEMBL11778122 | 0.78 | ABCB11 (0.43) | ABCB11AKR1C3AKR1C2PTGS1PTGS2 | |
| SCHEMBL9877199 | 0.76 | NQO1 (0.45) | TSHRLMNAMAPTKDM4ETDP1 | |
| SCHEMBL10982814 | 0.74 | ALOX5 (0.41) | AKR1C3AKR1C2PTGS1PTGS2TSHR | |
| SCHEMBL25316112 | 0.73 | ALDH1A1 (0.66) | LMNAMAPTKDM4ETDP1NPC1 | |
| SCHEMBL4868746 | 0.73 | TRPM8 (0.48) | TSHRALOX5LMNAMAPTNPC1 | |
| SCHEMBL4869949 | 0.73 | GSK3B (0.49) | TSHRLMNAMAPTNPC1TP53 | |
| Methane SCHEMBL11294998 | 0.72 | ABCB11 (0.42) | ABCB11AKR1C3AKR1C2PTGS1PTGS2 | |
| SCHEMBL8428661 | 0.71 | MTNR1A (0.46) | LMNATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3931269-A | ANTIINFLAMMATORY | WILLIAM H. RORER, INC. (US) | 1976-01-06 | — | — | US | disclosed |