Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.44 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11783471 | 0.89 | MEN1 (0.53) | MEN1KMT2AGAAGFERPOLB | |
| SCHEMBL11778072 | 0.85 | CA1 (0.46) | MEN1KMT2AGAAGFERPOLB | |
| SCHEMBL11780616 | 0.84 | PKM (0.59) | MEN1KMT2AGAAGFERBDKRB1 | |
| SCHEMBL11780536 | 0.83 | BDKRB1 (0.41) | MEN1KMT2AGAAGFERBDKRB1 | |
| SCHEMBL11780958 | 0.82 | CA1 (0.55) | MEN1KMT2AGAAGFERPOLB | |
| SCHEMBL11846740 | 0.81 | PTK2B (0.56) | MEN1KMT2AGAAGFERPOLB | |
| SCHEMBL11777201 | 0.79 | GAA (0.45) | MEN1KMT2AGAAPOLBMAPT | |
| SCHEMBL11844827 | 0.78 | LMNA (0.45) | KMT2APOLBPKMLMNATSHR | |
| SCHEMBL11781708 | 0.76 | MEN1 (0.48) | MEN1KMT2AGAAGFERPOLB | |
| SCHEMBL2883310 | 0.73 | KDM4E (0.52) | GAAGFERPOLBMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933906-A | DIURETIC | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |