Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11778072 | 0.91 | CA1 (0.46) | MEN1KMT2AGAAGFERPTGER4 | |
| SCHEMBL11780330 | 0.89 | MEN1 (0.47) | MEN1KMT2AGAAGFERCA12 | |
| SCHEMBL11780958 | 0.88 | CA1 (0.55) | MEN1KMT2AGAAGFERCA12 | |
| SCHEMBL11846740 | 0.86 | PTK2B (0.56) | MEN1KMT2AGAAGFERHTT | |
| SCHEMBL11782600 | 0.79 | MEN1 (0.43) | MEN1KMT2AGAAGFERPTGER4 | |
| SCHEMBL11782595 | 0.79 | MEN1 (0.43) | MEN1KMT2AGAAGFERPTGER4 | |
| SCHEMBL11781708 | 0.79 | MEN1 (0.48) | MEN1KMT2AGAAGFERPTGER4 | |
| SCHEMBL11850140 | 0.76 | CDC25B (0.46) | MEN1KMT2AGAAGFERCA12 | |
| SCHEMBL11846678 | 0.75 | GAA (0.56) | MEN1KMT2AGAAGFERCA12 | |
| SCHEMBL11846780 | 0.74 | CDC25B (0.41) | MEN1KMT2AGAAGFERCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933906-A | DIURETIC | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |