Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | FABP2 | P12104 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11788735 | 0.81 | CYP2A6 (0.53) | PTGS2PTGS1KMT2AAKR1C3AKR1C2 | |
| SCHEMBL11838674 | 0.81 | PTGS2 (0.41) | PTGS2PTGS1KMT2AAKR1C3AKR1C2 | |
| SCHEMBL11841932 | 0.81 | LMNA (0.57) | ALDH1A1MAPK1PTGS2PTGS1KMT2A | |
| SCHEMBL11844907 | 0.81 | HPGD (0.53) | ALDH1A1PTGS2PTGS1KMT2AAKR1C3 | |
| SCHEMBL11841900 | 0.80 | PTGS2 (0.40) | PTGS2PTGS1KMT2AAKR1C3AKR1C2 | |
| SCHEMBL11842067 | 0.80 | AKR1C3 (0.53) | ALDH1A1PTGS2PTGS1KMT2AAKR1C3 | |
| SCHEMBL11847394 | 0.80 | ALDH1A1 (0.52) | ALDH1A1PTGS2PTGS1KMT2AAKR1C3 | |
| SCHEMBL30057648 | 0.80 | ALDH1A1 (0.52) | ALDH1A1MAPK1PTGS2KMT2AMEN1 | |
| SCHEMBL11846562 | 0.80 | PPARG (0.49) | PTGS2PTGS1KMT2AAKR1C3AKR1C2 | |
| SCHEMBL11839188 | 0.80 | PTGS2 (0.59) | PTGS2PTGS1TSHRLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3969401-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC | WILLIAM H. RORER, INC. (US) | 1976-07-13 | — | — | US | disclosed |
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |