Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | FABP2 | P12104 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11846070 | 0.81 | LMNA (0.57) | ALDH1A1HSD17B10HDAC3HDAC4HDAC1 | |
| SCHEMBL11838674 | 0.81 | PTGS2 (0.41) | HDAC8PTGS2PTGS1KMT2AMEN1 | |
| SCHEMBL11844907 | 0.81 | HPGD (0.53) | ALDH1A1HSD17B10PTGS2PTGS1KMT2A | |
| SCHEMBL11788735 | 0.81 | CYP2A6 (0.53) | HSD17B10PTGS2PTGS1KMT2AMEN1 | |
| SCHEMBL11842067 | 0.80 | AKR1C3 (0.53) | ALDH1A1PTGS2L3MBTL1PTGS1KMT2A | |
| SCHEMBL11841900 | 0.80 | PTGS2 (0.40) | PTGS2PTGS1KMT2AMEN1HPGD | |
| SCHEMBL11846562 | 0.80 | PPARG (0.49) | PTGS2PTGS1KMT2AMEN1HPGD | |
| SCHEMBL11793687 | 0.80 | ALDH1A1 (0.52) | ALDH1A1PTGS2PTGS1KMT2AMEN1 | |
| SCHEMBL11839188 | 0.80 | PTGS2 (0.59) | PTGS2PTGS1TSHRLMNACYP1A2 | |
| SCHEMBL11836053 | 0.79 | ALDH1A1 (0.44) | ALDH1A1HSD17B10HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |