Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | PRKAB2 | O43741 | 4/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 4/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 4/20 | 0.42 |
| ▸ | PRKAG3 | Q9UGI9 | 4/20 | 0.42 |
| ▸ | PRKAG2 | Q9UGJ0 | 4/20 | 0.42 |
| ▸ | PRKAB1 | Q9Y478 | 4/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | FABP2 | P12104 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11788735 | 0.83 | CYP2A6 (0.53) | HPGDHSD17B10PTGS2PTGS1KMT2A | |
| SCHEMBL11838674 | 0.83 | PTGS2 (0.41) | HPGDPTGS2PTGS1KMT2AMEN1 | |
| SCHEMBL11793687 | 0.81 | ALDH1A1 (0.52) | HPGDALDH1A1PTGS2PTGS1KMT2A | |
| SCHEMBL11847394 | 0.81 | ALDH1A1 (0.52) | HPGDALDH1A1HSD17B10ADAMTS4PTGS2 | |
| SCHEMBL11841900 | 0.81 | PTGS2 (0.40) | HPGDPTGS2PTGS1KMT2AMEN1 | |
| SCHEMBL11842067 | 0.81 | AKR1C3 (0.53) | HPGDALDH1A1PTGS2PTGS1KMT2A | |
| SCHEMBL11846562 | 0.81 | PPARG (0.49) | HPGDPTGS2PTGS1KMT2AMEN1 | |
| SCHEMBL11839188 | 0.81 | PTGS2 (0.59) | PTGS2PTGS1CYP2C9CYP2C19TSHR | |
| SCHEMBL11838727 | 0.81 | LMNA (0.59) | HPGDALDH1A1BCL2L1HSD17B10ADAMTS4 | |
| SCHEMBL11841890 | 0.79 | ALDH1A1 (0.41) | HPGDALDH1A1BCL2L1HSD17B10ADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |