Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 7/20 | 0.60 |
| ▸ | TEAD4 | Q15561 | 2/20 | 0.57 |
| ▸ | YAP1 | P46937 | 1/20 | 0.57 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | CSF1R | P07333 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.52 |
| ▸ | KIT | P10721 | 1/20 | 0.52 |
| ▸ | FLT1 | P17948 | 1/20 | 0.52 |
| ▸ | FLT4 | P35916 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MPO | P05164 | 3/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flufenamic Acid SCHEMBL29438087 | 0.89 | RXFP1 (0.71) | RXFP1TEAD4YAP1TEAD2AURKA | |
| Flufenamic Acid SCHEMBL1478282 | 0.89 | RXFP1 (0.71) | RXFP1TEAD4YAP1TEAD2AURKA | |
| Flufenamic Acid SCHEMBL9845498 | 0.87 | RXFP1 (0.71) | RXFP1TEAD4YAP1TEAD2AURKA | |
| Flufenamic Acid SCHEMBL11524550 | 0.87 | RXFP1 (0.71) | RXFP1TEAD4YAP1TEAD2AURKA | |
| Flufenamic Acid SCHEMBL11788728 | 0.87 | RXFP1 (0.71) | RXFP1TEAD4YAP1TEAD2AURKA | |
| Flufenamic Acid SCHEMBL11793234 | 0.78 | RXFP1 (0.57) | RXFP1TEAD4YAP1TEAD2LMNA | |
| Flufenamic Acid SCHEMBL11791950 | 0.78 | RXFP1 (0.57) | RXFP1TEAD4YAP1TEAD2AURKA | |
| Flufenamic Acid SCHEMBL11791445 | 0.78 | RXFP1 (0.57) | RXFP1TEAD4YAP1TEAD2LMNA | |
| Flufenamic Acid SCHEMBL17497 | 0.77 | RXFP1 (0.75) | RXFP1TEAD4YAP1TEAD2AURKA | |
| Flufenamic Acid SCHEMBL29356958 | 0.77 | RXFP1 (0.75) | RXFP1TEAD4YAP1TEAD2AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3988333-A | Tri-substituted aluminum salts or di-substituted aluminum salts of carboxyl group-containing, pharmaceutically effective compounds | TEIKOKU HORMONE MFG. CO., LTD. (JA) | 1976-10-26 | — | — | US | disclosed |