Flufenamic Acid

Flufenamic Acid

SCHEMBL29356958

O=C(O)c1ccccc1Nc1cccc(C(F)(F)F)c1

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 2/20 0.75
MPO P05164 6/20 0.73
GRIK1 P39086 1/20 0.73
TEAD4 Q15561 2/20 0.71
YAP1 P46937 1/20 0.71
TEAD2 Q15562 1/20 0.71
TAS2R14 Q9NYV8 5/20 0.69
AURKA O14965 1/20 0.69
MAPK8 P45983 1/20 0.69
AKR1C3 P42330 2/20 0.68
AKR1C2 P52895 2/20 0.68
ADRA2B P18089 1/20 0.64
ADRA2C P18825 1/20 0.64
MEN1 O00255 1/20 0.64
GMNN O75496 1/20 0.64
ALDH1A1 P00352 1/20 0.64
LMNA P02545 1/20 0.64
TTR P02766 1/20 0.64
CYP1A2 P05177 1/20 0.64
CYP3A4 P08684 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flufenamic Acid SCHEMBL17497 1.00 RXFP1 (0.75) RXFP1MPOGRIK1TEAD4YAP1
Flufenamic Acid SCHEMBL11524554 0.99 RXFP1 (0.73) RXFP1MPOGRIK1TEAD4YAP1
Flufenamic Acid SCHEMBL9845499 0.99 RXFP1 (0.73) RXFP1MPOGRIK1TEAD4YAP1
SCHEMBL8416271 0.92 RXFP1 (0.81) RXFP1MPOGRIK1
Flufenamic Acid SCHEMBL10531046 0.89 MPO (0.67) RXFP1MPOGRIK1TEAD4YAP1
SCHEMBL19002050 0.89 TAS2R14 (0.62) RXFP1MPOGRIK1TEAD4YAP1
SCHEMBL11330727 0.88 TAS2R14 (0.82) RXFP1MPOGRIK1TAS2R14AKR1C3
SCHEMBL19657901 0.87 RXFP1 (0.70) RXFP1MPOGRIK1TEAD4YAP1
SCHEMBL9522037 0.87 YAP1 (0.74) RXFP1MPOGRIK1TEAD4YAP1
SCHEMBL12851592 0.87 RXFP1 (0.78) RXFP1MPOTEAD4YAP1TEAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 863 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121577796-A ROS (reactive oxygen species) high-efficiency synchronous identification system combining multiple molecular probes and application thereof 上海大学 2026-02-27 CN claimed
US-12485102-B2 Methods and compositions for treating cancer THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (US) 2025-12-02 US claimed
US-20250161330-A1 METHODS OF MEDICAL TREATMENT WITH SUR1-TRPM4 CHANNEL INHIBITORS REMEDY PHARMACEUTICALS, INC. (US) 2025-05-22 US claimed
CN-119997813-A Emulsifiable concentrate with lactone-based solvent system 巴斯夫欧洲公司 2025-05-13 CN claimed
CN-119744863-A Bactericide composition and application thereof 江苏中旗科技股份有限公司 2025-04-04 CN claimed
CN-119666767-A Environment-friendly detection method for trace heavy metal antimony in water 浙江工业大学 2025-03-21 CN claimed
CN-119110681-A Emulsifiable concentrate with (substituted) benzaldehyde-based solvent system 巴斯夫欧洲公司 2024-12-10 CN claimed
CN-112770764-B Methods of treating infections using bacteria 因达普特斯治疗有限公司 2024-12-03 CN claimed
CN-118973395-A Methods and compositions for controlling pests on perennial plants 环球化学股份有限公司 2024-11-15 CN claimed
CN-118870974-A Fungicidal combinations and methods for controlling phytopathogenic fungi UPL有限责任公司 2024-10-29 CN claimed
EP-4153870-A2 CYLINDER PISTON END CAP AND LOCK MECHANISM AT FULL SAFE LOAD THAT CAN BE INTEGRATED INTO HYDRAULIC AND PNEUMATIC CYLINDERS Ozel, Ali (TR) 2023-03-29 EP claimed
WO-2023023702-A1 MEDICATED SUPPLEMENT FOR ANIMALS Medical Ethics Pty Ltd (AU) 2023-03-02 WO claimed
US-20220403414-A1 NOVEL AAV VARIANT WUXI APPTEC SHANGHAI CO LTD (CN) 2022-12-22 US claimed
CN-218085817-U Bicycle saddle with adjustable multi-angle 唐山辰阳运动器材有限公司 2022-12-20 CN claimed
CN-217904673-U Coal mine underground double-link communication system 天津华宁电子有限公司 2022-11-25 CN claimed
US-20220281889-A1 SUBSTITUTED DIHYDROTHIENOPYRIMIDINES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS UNION therapeutics A/S (DK) 2022-09-08 US claimed
EP-4045664-A1 A NOVEL AAV VARIANT Wuxi Apptec (Shanghai) Co., Ltd. (CN) 2022-08-24 EP claimed
US-20220088039-A1 METHODS OF MEDICAL TREATMENT WITH SUR1-TRPM4 CHANNEL INHIBITORS BIOGEN CHESAPEAKE LLC (US) 2022-03-24 US claimed
CN-114172712-A Automatic upgrading equipment between networks 柴国丽 2022-03-11 CN claimed
US-20220031768-A1 METHODS OF TREATMENT OF INFECTIONS USING BACTERIA INDAPTUS THERAPEUTICS, INC. 2022-02-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220281889-A1 SUBSTITUTED DIHYDROTHIENOPYRIMIDINES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS PDE4A, PDE7A, PDE12 RXFP1 2669/4885MPO 195/4885GRIK1 4038/4885
US-12485102-B2 Methods and compositions for treating cancer PPARG, FFAR1, PPARA RXFP1 2201/4885MPO 3889/4885GRIK1 2067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.