Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 9/20 | 0.71 |
| ▸ | YAP1 | P46937 | 1/20 | 0.68 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.68 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.68 |
| ▸ | MPO | P05164 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.55 |
| ▸ | AURKA | O14965 | 1/20 | 0.54 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flufenamic Acid SCHEMBL29438087 | 1.00 | RXFP1 (0.71) | RXFP1YAP1TEAD4TEAD2MPO | |
| Flufenamic Acid SCHEMBL9845498 | 0.97 | RXFP1 (0.71) | RXFP1YAP1TEAD4TEAD2MPO | |
| Flufenamic Acid SCHEMBL11788728 | 0.97 | RXFP1 (0.71) | RXFP1YAP1TEAD4TEAD2MPO | |
| Flufenamic Acid SCHEMBL11524550 | 0.97 | RXFP1 (0.71) | RXFP1YAP1TEAD4TEAD2MPO | |
| Flufenamic Acid SCHEMBL11794349 | 0.89 | RXFP1 (0.60) | RXFP1YAP1TEAD4TEAD2MPO | |
| Flufenamic Acid SCHEMBL11791445 | 0.88 | RXFP1 (0.57) | RXFP1YAP1TEAD4TEAD2MPO | |
| Flufenamic Acid SCHEMBL11791950 | 0.88 | RXFP1 (0.57) | RXFP1YAP1TEAD4TEAD2MPO | |
| Flufenamic Acid SCHEMBL11793234 | 0.88 | RXFP1 (0.57) | RXFP1YAP1TEAD4TEAD2MPO | |
| Flufenamic Acid SCHEMBL17497 | 0.86 | RXFP1 (0.75) | RXFP1YAP1TEAD4TEAD2MPO | |
| Flufenamic Acid SCHEMBL29356958 | 0.86 | RXFP1 (0.75) | RXFP1YAP1TEAD4TEAD2MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3988333-A | Tri-substituted aluminum salts or di-substituted aluminum salts of carboxyl group-containing, pharmaceutically effective compounds | TEIKOKU HORMONE MFG. CO., LTD. (JA) | 1976-10-26 | — | — | US | claimed |
| EP-1860158-B1 | Particles comprising a substrate and an anion-binding layer | MERCK PATENT GMBH (DE) | 2013-12-04 | — | — | EP | disclosed |
| US-7914893-B2 | Particles comprising an anion-binding layer containing anion-forming organic active compounds, and method of making and using thereof | MERCK PATENT GMBH (DE) | 2011-03-29 | — | — | US | disclosed |
| US-20070275244-A1 | Particles | MERCK PATENT GMBH | 2007-11-29 | — | — | US | disclosed |
| EP-1860158-A2 | Particles comprising a substrate and an anion-binding layer | MERCK PATENT GmbH (DE) | 2007-11-28 | — | — | EP | disclosed |
| US-3988333-A | Tri-substituted aluminum salts or di-substituted aluminum salts of carboxyl group-containing, pharmaceutically effective compounds | TEIKOKU HORMONE MFG. CO., LTD. (JA) | 1976-10-26 | — | — | US | disclosed |