Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CCR3 | P51677 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.32 |
| ▸ | LSS | P48449 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 3/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2885366 | 0.81 | CHRM2 (0.38) | CARM1PRMT6ROCK2ROCK1CDC42BPB | |
| SCHEMBL19575592 | 0.81 | CHRM2 (0.38) | CARM1PRMT6ROCK2ROCK1CDC42BPB | |
| SCHEMBL13874675 | 0.77 | DPP4 (0.38) | L3MBTL1SIGMAR1 | |
| SCHEMBL13874672 | 0.77 | DPP4 (0.38) | L3MBTL1SIGMAR1 | |
| SCHEMBL13325440 | 0.73 | — | — | |
| SCHEMBL90794 | 0.73 | — | — | |
| SCHEMBL4328940 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL31505915 | 0.71 | NCF1 (0.43) | CARM1PRMT6L3MBTL1KDM1A | |
| SCHEMBL24196665 | 0.71 | RPS6KB1 (0.36) | CARM1PRMT6ROCK2ROCK1CDC42BPB | |
| SCHEMBL23943527 | 0.70 | USP1 (0.32) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240458-B1 | ARYL SULFONAMIDES AS EFFECTIVE ANALGESICS | BOEHRINGER INGELHEIM INT (DE) | 2011-08-03 | — | — | EP | disclosed |
| US-20110046106-A1 | ARYL SULFONAMIDES AS EFFECTIVE ANALGESICS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046106-A1 | ARYL SULFONAMIDES AS EFFECTIVE ANALGESICS | SULT2A1, SULT1A1, ARSA | ALDH1A1 60/4885CCR3 1063/4885BCHE 1828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.