Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11780536 | 0.88 | BDKRB1 (0.41) | GAAALDH1A1RAB9AKMT2APOLB | |
| SCHEMBL11780923 | 0.87 | ALDH1A1 (0.51) | GAAALDH1A1MAPTRAB9AUSP2 | |
| SCHEMBL11781725 | 0.84 | GAA (0.43) | GAAMAPK1ALDH1A1MAPTRAB9A | |
| SCHEMBL11777521 | 0.82 | ALDH1A1 (0.45) | GAAMAPK1ALDH1A1MAPTRAB9A | |
| SCHEMBL11838980 | 0.82 | ALDH1A1 (0.47) | GAAMAPK1ALDH1A1MAPTRAB9A | |
| SCHEMBL11781708 | 0.81 | MEN1 (0.48) | GAAALDH1A1MAPTKMT2APOLB | |
| SCHEMBL11780330 | 0.79 | MEN1 (0.47) | GAAMAPTKMT2APOLBSMN1; SMN2 | |
| SCHEMBL11778805 | 0.77 | ALDH1A1 (0.53) | GAAMAPK1ALDH1A1MAPTRAB9A | |
| SCHEMBL11780616 | 0.76 | PKM (0.59) | GAAALDH1A1MAPTKMT2APOLB | |
| SCHEMBL11796927 | 0.75 | ALDH1A1 (0.42) | GAAALDH1A1MAPTRAB9AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933906-A | DIURETIC | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |