Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.38 |
| ▸ | WNT3A | P56704 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11679975 | 0.86 | KDM4E (0.52) | ALDH1A1HPGDMAPTKDM4EL3MBTL1 | |
| SCHEMBL11554619 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAOBHPGDMAPTHSD17B10 | |
| SCHEMBL11797647 | 0.79 | HPGD (0.41) | ALDH1A1HPGDKDM4ECTNNB1WNT3A | |
| SCHEMBL11803305 | 0.77 | MAOB (0.64) | ALDH1A1MAOBHPGDMAPTHSD17B10 | |
| SCHEMBL11729199 | 0.76 | L3MBTL1 (0.61) | ALDH1A1MAOBHPGDMAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL11748357 | 0.76 | MAOB (0.65) | ALDH1A1MAOBHPGDMAPTHSD17B10 | |
| SCHEMBL11751985 | 0.75 | KDM4E (0.67) | ALDH1A1MAOBHPGDMAPTHSD17B10 | |
| SCHEMBL11798128 | 0.75 | TRPV1 (0.37) | KDM4EMEN1KMT2A | |
| SCHEMBL11800382 | 0.75 | CHRM2 (0.45) | ALDH1A1MAOBHPGDMAPTHSD17B10 | |
| SCHEMBL11794977 | 0.74 | L3MBTL1 (0.59) | ALDH1A1MAOBHPGDMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957989-A | ADMINISTERING | RICHARDSON-MERRELL INC. (US) | 1976-05-18 | — | — | US | disclosed |