Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1D | Q01668 | 9/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | DHFR | P00374 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11806148 | 0.86 | ALDH1A1 (0.61) | CACNA1DKDM4EGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL11802006 | 0.86 | CACNA1D (0.77) | CACNA1DADORA3KDM4EGAADHFR | |
| SCHEMBL11800413 | 0.85 | CACNA1D (0.51) | CACNA1DKDM4EALDH1A1 | |
| SCHEMBL11803207 | 0.84 | CA1 (0.50) | CACNA1DADORA3KDM4EGAAALDH1A1 | |
| SCHEMBL11007804 | 0.83 | TSHR (0.54) | CACNA1DADORA3KDM4EGAAALDH1A1 | |
| SCHEMBL11669396 | 0.81 | ADORA3 (0.68) | CACNA1DADORA3KDM4EGAADHFR | |
| SCHEMBL10684386 | 0.78 | ADORA3 (0.75) | CACNA1DADORA3KDM4EGAADHFR | |
| SCHEMBL11800038 | 0.76 | CACNA1D (0.62) | CACNA1D | |
| SCHEMBL11670650 | 0.75 | ADORA3 (0.59) | CACNA1DADORA3KDM4EGAADHFR | |
| SCHEMBL10346121 | 0.75 | KDM4E (0.58) | CACNA1DADORA3KDM4EGAADHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3989708-A | HYPOTENSIVE, CORONARY VESSEL DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-02 | — | — | US | disclosed |