Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 10/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14350114 | 0.79 | GPR35 (0.35) | GPR35RAPGEF4SRCABL1BCR | |
| SCHEMBL14376109 | 0.79 | PGK1 (0.49) | GPR35RAPGEF4SRCPGK1ADORA1 | |
| SCHEMBL2090288 | 0.78 | RAPGEF4 (0.46) | RAPGEF4SRCHPGDALDH1A1 | |
| SCHEMBL23689911 | 0.77 | AR (0.42) | RAPGEF4ALDH1A1 | |
| SCHEMBL10429296 | 0.72 | TTR (0.37) | GPR35SLC6A4SLC6A3KCNH2 | |
| SCHEMBL1340231 | 0.72 | ALDH1A1 (0.56) | GPR35TRPV4HPGDALDH1A1SLC6A3 | |
| SCHEMBL8111333 | 0.72 | GPR35 (0.41) | GPR35TRPV4PGK1HPGDALDH1A1 | |
| SCHEMBL16119585 | 0.72 | SRC (0.43) | SRCTRPV4HPGDALDH1A1KCNH2 | |
| SCHEMBL1922370 | 0.72 | PRKCQ (0.39) | SRCABL1BCRPGK1PRKCQ | |
| SCHEMBL3077861 | 0.72 | ALDH1A1 (0.52) | GPR35TRPV4HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3987192-A | ANTIALLERGENS AND ANTIANAPHYLAXID; 2'-CYANO-OXANILIC ACID | THE UPJOHN COMPANY (US) | 1976-10-19 | — | — | US | disclosed |