Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | MDM4 | O15151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11804273 | 0.80 | RAB9A (0.45) | AGTR1RAB9AALDH1A1HPGDKMT2A | |
| SCHEMBL9716704 | 0.80 | KDM4E (0.49) | AGTR1KDM4ERAB9AALDH1A1HPGD | |
| SCHEMBL11800788 | 0.77 | KDM4E (0.46) | AGTR1KDM4ERAB9AALDH1A1HPGD | |
| SCHEMBL11819594 | 0.77 | KDM4E (0.46) | AGTR1KDM4ERAB9AALDH1A1HPGD | |
| SCHEMBL10505335 | 0.75 | MME (0.48) | ALDH1A1HPGDHSD17B10KMT2AMEN1 | |
| SCHEMBL698881 | 0.74 | AGTR1 (0.60) | AGTR1KDM4ERAB9AALDH1A1HPGD | |
| SCHEMBL8074247 | 0.73 | LARS1 (0.44) | AGTR1KDM4ERAB9AALDH1A1HPGD | |
| SCHEMBL6303080 | 0.72 | AGTR1 (0.44) | AGTR1KDM4ERAB9AALDH1A1HPGD | |
| SCHEMBL690246 | 0.72 | KDM4E (0.53) | AGTR1KDM4ERAB9AALDH1A1HPGD | |
| SCHEMBL5967407 | 0.72 | KDM4E (0.50) | AGTR1KDM4ERAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3971828-A | METABOLISM, PROPHYLAXIS | SANTEN PHARMACEUTICAL CO. LTD. (JA) | 1976-07-27 | — | — | US | disclosed |