Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11807540 | 0.83 | CSNK1E (0.34) | AURKAKDRAURKBDYRK1A | |
| SCHEMBL11806507 | 0.83 | TDP1 (0.40) | AURKAKDRAURKBNPC1RAB9A | |
| SCHEMBL11806977 | 0.80 | HSD11B1 (0.34) | HSD11B1CDK9DYRK1A | |
| SCHEMBL11812193 | 0.74 | MBOAT4 (0.32) | HSD11B1AURKAKDRAURKB | |
| SCHEMBL11811391 | 0.74 | ADORA3 (0.32) | AURKAKDRAURKB | |
| SCHEMBL11815308 | 0.71 | CFTR (0.32) | AURKAKDRAURKB | |
| SCHEMBL11804831 | 0.68 | TDP1 (0.39) | NPC1RAB9A | |
| SCHEMBL11818281 | 0.67 | KDM4E (0.40) | NPC1RAB9ACDK9DYRK1A | |
| SCHEMBL22927077 | 0.67 | CFTR (0.39) | AURKAKDRAURKBRAB9AACHE | |
| SCHEMBL11806359 | 0.66 | LMNA (0.38) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954438-A | 5-Trifluoromethyl-7-aminobenzimidazoles herbicides | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |