Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.32 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.32 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | CLK3 | P49761 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11805651 | 0.86 | CDK9 (0.40) | KMT2AMEN1PKMCDK9DYRK1A | |
| SCHEMBL11517572 | 0.86 | KDM4E (0.40) | KMT2AMEN1PKMCDK9DYRK1A | |
| SCHEMBL11804036 | 0.85 | TLR8 (0.38) | KMT2AMEN1PKMCDK9DYRK1A | |
| SCHEMBL11812652 | 0.82 | CHRNB2 (0.36) | KMT2AMEN1PKMCDK9DYRK1A | |
| SCHEMBL11806977 | 0.81 | HSD11B1 (0.34) | KMT2AMEN1PKMCDK9DYRK1A | |
| SCHEMBL11812366 | 0.76 | ADRB2 (0.30) | — | |
| SCHEMBL11809102 | 0.75 | CSNK1E (0.36) | DYRK1ADYRK2CSNK1ECLK1CLK2 | |
| SCHEMBL11812544 | 0.75 | — | — | |
| SCHEMBL11803727 | 0.75 | KDM4E (0.40) | KMT2ACDK9DYRK1ADYRK2CSNK1E | |
| SCHEMBL11810909 | 0.75 | GRM2 (0.35) | DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954438-A | 5-Trifluoromethyl-7-aminobenzimidazoles herbicides | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |