Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 3/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69429 | 0.70 | ACHE (0.59) | ESR1ESR2HSD17B10CYP3A4ACHE | |
| SCHEMBL11320317 | 0.69 | ESR1 (0.56) | ESR1ESR2HSD17B10CYP3A4HPGD | |
| SCHEMBL4132562 | 0.69 | HDAC4 (0.37) | HSD17B10CYP3A4HPGDCRHBPCRHR2 | |
| SCHEMBL298773 | 0.68 | MEN1 (0.41) | ESR1ESR2HSD17B10HPGDACHE | |
| SCHEMBL4132565 | 0.67 | ERN1 (0.33) | HSD17B10CYP3A4HPGDCRHBPCRHR2 | |
| SCHEMBL4245311 | 0.67 | ACHE (0.55) | ESR1ESR2HSD17B10CYP3A4HPGD | |
| SCHEMBL8859642 | 0.66 | CYP3A4 (0.34) | ESR1ESR2HSD17B10CYP3A4HPGD | |
| SCHEMBL68775 | 0.65 | ESR1 (0.62) | ESR1ESR2HSD17B10ACHEPDE7A | |
| SCHEMBL8015643 | 0.65 | CYP3A4 (0.38) | ESR1HSD17B10CYP3A4HPGDCRHBP | |
| SCHEMBL9539224 | 0.65 | ALDH1A1 (0.48) | ESR1ESR2HSD17B10CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3948856-A | Acid interchange polymerization process for producing an aromatic polyester | CELANESE CORPORATION (US) | 1976-04-06 | — | — | US | disclosed |