Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 9/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.59 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 4/20 | 0.54 |
| ▸ | TEK | Q02763 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11366152 | 0.90 | LMNA (0.62) | LMNACYP1A2HIF1ASMN1; SMN2CYP2C19 | |
| SCHEMBL11809362 | 0.87 | LMNA (0.51) | LMNACYP1A2HIF1ASMN1; SMN2CYP2C19 | |
| SCHEMBL9882802 | 0.86 | LMNA (0.82) | LMNACYP1A2HIF1ASMN1; SMN2CYP2C19 | |
| SCHEMBL30704747 | 0.86 | LMNA (0.57) | LMNACYP1A2HIF1ASMN1; SMN2CYP2C19 | |
| SCHEMBL10816027 | 0.86 | LMNA (0.57) | LMNACYP1A2HIF1ASMN1; SMN2CYP2C19 | |
| SCHEMBL24359625 | 0.85 | LMNA (0.67) | LMNACYP1A2HIF1ASMN1; SMN2CYP2C19 | |
| Fenbendazole SCHEMBL166352 | 0.85 | LMNA (0.82) | LMNACYP1A2HIF1ASMN1; SMN2CYP2C19 | |
| Fenbendazole SCHEMBL31547327 | 0.85 | LMNA (0.82) | LMNACYP1A2HIF1ASMN1; SMN2CYP2C19 | |
| SCHEMBL10742639 | 0.85 | LMNA (0.56) | LMNACYP1A2HIF1ASMN1; SMN2CYP2C19 | |
| Fenbendazole SCHEMBL31547342 | 0.85 | LMNA (0.82) | LMNACYP1A2HIF1ASMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10813914-B2 | Composition for controlling microsporidia in fishes and method for controlling microsporidia in fishes using same | MARUHA NICHIRO CORPORATION (JP) | 2020-10-27 | — | — | US | disclosed |
| US-20190111027-A1 | COMPOSITION FOR CONTROLLING MICROSPORIDIA IN FISHES AND METHOD FOR CONTROLLING MICROSPORIDIA IN FISHES USING SAME | MARUHA NICHIRO CORPORATION (JP) | 2019-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10813914-B2 | Composition for controlling microsporidia in fishes and method for controlling microsporidia in fishes using same | MUSK, MRM1, RRS1 | LMNA 3483/4885CYP1A2 164/4885HIF1A 3724/4885 |
| US-20190111027-A1 | COMPOSITION FOR CONTROLLING MICROSPORIDIA IN FISHES AND METHOD FOR CONTROLLING MICROSPORIDIA IN FISHES USING SAME | MUSK, MRM1, RRS1 | LMNA 3483/4885CYP1A2 164/4885HIF1A 3724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.