Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.72 |
| ▸ | RXRB | P28702 | 2/20 | 0.72 |
| ▸ | RXRG | P48443 | 2/20 | 0.72 |
| ▸ | MAOB | P27338 | 9/20 | 0.59 |
| ▸ | MAOA | P21397 | 6/20 | 0.59 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL694229 | 0.84 | RXRA (1.00) | RXRARXRBRXRGMAOBMAOA | |
| SCHEMBL11807045 | 0.84 | MAOB (0.70) | RXRARXRBMAOBMAOANR4A2 | |
| SCHEMBL11810982 | 0.84 | ALDH1A1 (0.60) | RXRARXRBMAOBNR4A2NR4A1 | |
| SCHEMBL694037 | 0.83 | RXRA (0.72) | RXRARXRBRXRGMAOBMAOA | |
| SCHEMBL11526892 | 0.81 | NAAA (0.51) | RXRARXRBRXRGMAOBMAOA | |
| SCHEMBL28510237 | 0.79 | RXRA (0.59) | RXRARXRBRXRGMAOBMAOA | |
| SCHEMBL27676289 | 0.79 | RXRA (0.69) | RXRARXRBRXRGMAOBMAOA | |
| SCHEMBL365115 | 0.78 | RXRA (0.64) | RXRARXRBRXRGMAOBMAOA | |
| SCHEMBL15189660 | 0.78 | MAOB (0.69) | RXRARXRBMAOBNR4A2NR4A1 | |
| Methyl Alcohol SCHEMBL27542849 | 0.77 | RXRA (0.68) | RXRARXRBRXRGMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3978132-A | HYPOLIPIDEMIC | SANDOZ, INC. (US) | 1976-08-31 | — | — | US | claimed |
| US-3978132-A | HYPOLIPIDEMIC | SANDOZ, INC. (US) | 1976-08-31 | — | — | US | disclosed |