Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.46 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11530823 | 0.84 | ELANE (0.56) | PARP15PARP14PARP10CYP2C9RAB9A | |
| SCHEMBL2775115 | 0.83 | MAPT (0.63) | NAAAMGLLRXRARXRBRXRG | |
| SCHEMBL24799711 | 0.82 | PARP10 (0.58) | POLBPARP10NPC1RAB9A | |
| SCHEMBL8357803 | 0.82 | PARP10 (0.58) | POLBPARP10NPC1RAB9A | |
| SCHEMBL24813408 | 0.82 | HPGD (0.58) | PARP15PARP14PARP10NPC1RAB9A | |
| SCHEMBL11809581 | 0.81 | RXRA (0.72) | POLBRXRARXRBRXRGNPC1 | |
| SCHEMBL19612714 | 0.81 | NAAA (0.56) | NAAAMGLLRXRARXRBRXRG | |
| SCHEMBL30982340 | 0.81 | RXRA (0.63) | NAAARXRARXRBRXRGTNKS | |
| SCHEMBL15011761 | 0.81 | RXRA (0.63) | NAAARXRARXRBRXRGTNKS | |
| SCHEMBL10996319 | 0.81 | NAAA (0.56) | NAAAMGLLRXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4175138-A | α-Alkyl-p-phenoxy benzyl alcohols, compositions and treating lipidemia | SANDOZ, INC. (US) | 1979-11-20 | — | — | US | disclosed |
| US-4085149-A | HYPOLIPIDEMIC | SANDOZ, INC. (US) | 1978-04-18 | — | — | US | disclosed |
| US-4065503-A | HYPOLIPIDEMIC AGENTS | SANDOZ, INC. (US) | 1977-12-27 | — | — | US | disclosed |
| US-3997567-A | HYPOLIPIDEMIC | SANDOZ, INC. (US) | 1976-12-14 | — | — | US | disclosed |
| US-3962459-A | Lipidemia treatment with p-phenoxy-alkylphenone compositions | SANDOZ, INC. (US) | 1976-06-08 | — | — | US | disclosed |
| US-3946119-A | Optionally substituted α-tertiary butyl-p-phenoxybenzylamines and their use as hypolipidemic agents | SANDOZ, INC. (US) | 1976-03-23 | — | — | US | disclosed |