Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 9/20 | 0.59 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.59 |
| ▸ | GABRA2 | P47869 | 8/20 | 0.59 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.59 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.56 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.56 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11731330 | 0.85 | GABRA3 (0.64) | GABRA5GABRA1GABRA2GABRB2GABRA3 | |
| SCHEMBL11734238 | 0.85 | OPRK1 (0.67) | GABRA5GABRA1GABRA2GABRB2GABRA3 | |
| SCHEMBL11730151 | 0.85 | OPRK1 (0.48) | GABRA5GABRA1GABRA2GABRB2GABRA3 | |
| SCHEMBL11830831 | 0.84 | GABRA1 (0.49) | GABRA5GABRA1GABRA2GABRB2GABRA3 | |
| SCHEMBL11735029 | 0.84 | GABRA1 (0.61) | GABRA5GABRA1GABRA2GABRB2GABRA3 | |
| SCHEMBL9565432 | 0.84 | GABRA5 (0.50) | GABRA5GABRA1GABRA2GABRB2GABRA3 | |
| SCHEMBL11845687 | 0.82 | CHRM1 (0.49) | GABRA5GABRA1GABRA2GABRB2GABRA3 | |
| SCHEMBL11830483 | 0.82 | GABRA1 (0.58) | GABRA5GABRA1GABRA2GABRB2GABRA3 | |
| SCHEMBL11825387 | 0.82 | CHRM1 (0.49) | GABRA5GABRA1GABRA2GABRB2GABRA3 | |
| SCHEMBL10471068 | 0.82 | GABRA1 (0.59) | GABRA5GABRA1GABRA2GABRB2GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941803-A | 2-(Imidazol-1-yl)benzophenones | THE UPJOHN COMPANY (US) | 1976-03-02 | — | — | US | disclosed |
| US-3933794-A | CENTRAL NERVOUS SYSTEM DEPRESSANTS | THE UPJOHN COMPANY (US) | 1976-01-20 | — | — | US | disclosed |