Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7678834 | 0.86 | HPGD (0.48) | KMT2ASMN1; SMN2HTTSRD5A2MAPK1 | |
| SCHEMBL11813331 | 0.82 | CA1 (0.49) | KMT2AMAPK1HPGDMAPTALDH1A1 | |
| SCHEMBL11815696 | 0.82 | MMP1 (0.43) | KMT2ASMN1; SMN2HTTSRD5A2MAPK1 | |
| SCHEMBL11810726 | 0.81 | HPGD (0.47) | KMT2ASRD5A2MAPK1HPGDMAPT | |
| SCHEMBL7678669 | 0.77 | NPC1 (0.41) | KMT2ASMN1; SMN2HTTSRD5A2MAPK1 | |
| SCHEMBL9792211 | 0.74 | SRD5A2 (0.50) | KMT2ASMN1; SMN2HTTSRD5A2MAPK1 | |
| SCHEMBL10939169 | 0.73 | SRD5A2 (0.59) | KMT2ASMN1; SMN2HTTSRD5A2MAPK1 | |
| SCHEMBL9792285 | 0.71 | KMT2A (0.48) | KMT2ASMN1; SMN2HTTSRD5A2MAPK1 | |
| SCHEMBL7678571 | 0.70 | SRD5A2 (0.46) | KMT2ASRD5A2HPGDALDH1A1L3MBTL1 | |
| SCHEMBL7674517 | 0.70 | LTA4H (0.43) | SRD5A2HPGDALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3952012-A | MULTISTAGE | MCNEIL LABORATORIES, INCORPORATED (US) | 1976-04-20 | — | — | US | disclosed |