Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.49 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7676938 | 0.87 | MAPT (0.52) | CA1CA2ALDH1A1GAAMAPT | |
| SCHEMBL11814720 | 0.82 | SIRT1 (0.47) | ALDH1A1MAPTRAB9AMEN1LMNA | |
| SCHEMBL7685125 | 0.80 | RAB9A (0.53) | CA1CA2ALDH1A1GAAMAPT | |
| SCHEMBL9792216 | 0.75 | HPGD (0.59) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL3997292 | 0.73 | ALDH1A1 (0.43) | ALDH1A1GAAMAPTRAB9AMEN1 | |
| SCHEMBL8518752 | 0.72 | BRD4 (0.39) | CA2ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL11810726 | 0.72 | HPGD (0.47) | ALDH1A1MAPTRAB9AMAPK1KMT2A | |
| SCHEMBL11813950 | 0.72 | TSHR (0.45) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL1764282 | 0.71 | ALDH1A1 (0.47) | ALDH1A1GAAMAPTRAB9AMEN1 | |
| SCHEMBL15943729 | 0.71 | ALDH1A1 (0.47) | ALDH1A1GAARAB9ALMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3952012-A | MULTISTAGE | MCNEIL LABORATORIES, INCORPORATED (US) | 1976-04-20 | — | — | US | disclosed |