Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.45 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PTPRG | P23470 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11820641 | 0.86 | AKR1C3 (0.52) | AKR1C3LMNACA12CA9CA1 | |
| SCHEMBL11820489 | 0.85 | PTPRC (0.46) | LMNACA12CA9CA1CA2 | |
| SCHEMBL11820442 | 0.85 | PTPRC (0.46) | LMNACA12CA9CA1CA2 | |
| SCHEMBL11826205 | 0.82 | PTPRC (0.47) | CA12CA9CA1CA2CA6 | |
| SCHEMBL11817253 | 0.79 | PTPRG (0.52) | LMNACA2PTPRCPTPRGGAA | |
| SCHEMBL11818315 | 0.78 | AKR1C3 (0.54) | AKR1C3LMNACA12CA9CA1 | |
| SCHEMBL11819921 | 0.74 | CNR2 (0.48) | LMNACA12CA9CA2ALDH1A1 | |
| SCHEMBL11822163 | 0.74 | CA2 (0.47) | CA12CA9CA1CA2CA6 | |
| SCHEMBL11818580 | 0.74 | CA2 (0.47) | CA12CA9CA1CA2CA6 | |
| SCHEMBL31014170 | 0.73 | LMNA (0.56) | LMNAPDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |