Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11814852 | 0.78 | AKR1C3 (0.48) | AKR1C3LMNAMAPTALDH1A1CA12 | |
| SCHEMBL11826895 | 0.77 | PTPRC (0.46) | AKR1C3LMNAMAPTMEN1KMT2A | |
| SCHEMBL11820641 | 0.75 | AKR1C3 (0.52) | AKR1C3LMNAMAPTCA12CA9 | |
| SCHEMBL11822234 | 0.74 | L3MBTL1 (0.57) | LMNAMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL13802466 | 0.72 | MRGPRX4 (0.63) | AKR1C3MAPTARMRGPRX4PTPRC | |
| SCHEMBL11815605 | 0.72 | CA12 (0.46) | MAPTMEN1ALDH1A1KMT2ACA12 | |
| SCHEMBL11816193 | 0.71 | KMT2A (0.44) | MAPTMEN1KMT2ACA12CA9 | |
| SCHEMBL693069 | 0.71 | RXRA (0.57) | LMNAMAPTMEN1KMT2AAR | |
| SCHEMBL11827713 | 0.70 | KMT2A (0.43) | MEN1KMT2ACYP2C19CA12CA9 | |
| SCHEMBL31014170 | 0.69 | LMNA (0.56) | LMNAMEN1ALDH1A1KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |