Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | IL1RN | P18510 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11818628 | 0.87 | L3MBTL1 (0.58) | L3MBTL1MAPTIL1RNALDH1A1MEN1 | |
| SCHEMBL11821935 | 0.80 | L3MBTL1 (0.60) | L3MBTL1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11820807 | 0.80 | TDP1 (0.56) | L3MBTL1MAPTIL1RNMEN1KMT2A | |
| SCHEMBL11817881 | 0.80 | L3MBTL1 (0.59) | L3MBTL1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11826895 | 0.79 | PTPRC (0.46) | L3MBTL1MAPTMEN1KMT2ALMNA | |
| SCHEMBL11818278 | 0.78 | L3MBTL1 (0.54) | L3MBTL1MAPTIL1RNALDH1A1MEN1 | |
| SCHEMBL11818315 | 0.74 | AKR1C3 (0.54) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL13802466 | 0.73 | MRGPRX4 (0.63) | MAPTCYP2C9HPGDRAB9AAR | |
| SCHEMBL693069 | 0.72 | RXRA (0.57) | MAPTMEN1KMT2ALMNAHPGD | |
| SCHEMBL15952845 | 0.72 | LMNA (0.71) | L3MBTL1ALDH1A1KMT2ALMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |