Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19010188 | 0.87 | TP53 (0.60) | TP53GAAKMT2ALMNAMAPT | |
| SCHEMBL11822995 | 0.84 | KDM4E (0.63) | TP53GAAKCNMA1KMT2ALMNA | |
| SCHEMBL9539984 | 0.80 | CASP1 (0.58) | TP53GAALMNAMAPTHTT | |
| SCHEMBL18196076 | 0.80 | LMNA (0.50) | TP53KCNMA1KMT2ALMNAMAPT | |
| SCHEMBL6097936 | 0.79 | MAPT (0.49) | TP53KCNMA1KMT2ALMNAMAPT | |
| SCHEMBL14099187 | 0.79 | LMNA (0.50) | TP53KCNMA1KMT2ALMNAMAPT | |
| SCHEMBL405878 | 0.79 | HDAC1 (0.65) | GAAKMT2ALMNAMAPTHTT | |
| SCHEMBL14822784 | 0.79 | KMT2A (0.53) | GAAKMT2AMAPTHDAC1HDAC6 | |
| SCHEMBL23884641 | 0.78 | CASP1 (0.44) | TP53KCNMA1KMT2ALMNAMAPT | |
| SCHEMBL7001348 | 0.77 | KDM4E (0.67) | KMT2AMAPTHTTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4503073-A | ANTIINFLAMMATORY, ANALGESIC, ANTICOAGULANT | A. H. ROBINS COMPANY, INCORPORATED (US) | 1985-03-05 | — | — | US | disclosed |