Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | FABP2 | P12104 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11837086 | 0.86 | BACE1 (0.44) | PTGS1KMT2ALMNATSHRHPGD | |
| SCHEMBL11823054 | 0.84 | CSNK2A1 (0.53) | KMT2AMMP2MMP3HCAR2 | |
| SCHEMBL11827837 | 0.83 | PPARG (0.49) | MEN1KMT2ALMNAMMP2MMP3 | |
| SCHEMBL11821466 | 0.83 | CD274 (0.39) | PTGS1KMT2ALMNATSHRBACE1 | |
| SCHEMBL11829226 | 0.83 | FOLH1 (0.41) | PTGS1KMT2ALMNATSHRBACE1 | |
| SCHEMBL11828303 | 0.83 | ADAMTS4 (0.41) | PTGS1KMT2ALMNATSHRBACE1 | |
| SCHEMBL11832248 | 0.83 | KMT2A (0.39) | PTGS1KMT2ALMNATSHRBACE1 | |
| SCHEMBL11831544 | 0.83 | MMP2 (0.47) | AKR1C3AKR1C2MMP2MMP3S1PR1 | |
| SCHEMBL11830550 | 0.81 | FOLH1 (0.46) | PTGS1MEN1KMT2APTGS2FABP2 | |
| SCHEMBL11827462 | 0.80 | CYP19A1 (0.44) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |