Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 10/20 | 0.44 |
| ▸ | MMP3 | P08254 | 6/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 4/20 | 0.42 |
| ▸ | MMP14 | P50281 | 4/20 | 0.42 |
| ▸ | MMP13 | P45452 | 3/20 | 0.42 |
| ▸ | MMP1 | P03956 | 3/20 | 0.42 |
| ▸ | BMP1 | P13497 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11837086 | 0.86 | BACE1 (0.44) | MMP2MMP9MMP14MMP13LMNA | |
| SCHEMBL11823054 | 0.84 | CSNK2A1 (0.53) | MMP2MMP3MMP9MMP14MMP13 | |
| SCHEMBL11827993 | 0.84 | PPARG (0.50) | PPARGPPARAMMP2MMP3ESR2 | |
| SCHEMBL11830550 | 0.84 | FOLH1 (0.46) | PPARGPPARAMMP2MMP9MMP14 | |
| SCHEMBL11832248 | 0.83 | KMT2A (0.39) | PPARGPPARAMMP2MMP9MMP14 | |
| SCHEMBL11821466 | 0.83 | CD274 (0.39) | MMP2MMP3MMP9MMP14MMP13 | |
| SCHEMBL11828303 | 0.83 | ADAMTS4 (0.41) | PPARGPPARAMMP2MMP9MMP14 | |
| SCHEMBL11829226 | 0.83 | FOLH1 (0.41) | PPARGPPARAMMP2MMP9MMP14 | |
| SCHEMBL11837826 | 0.83 | PTGS1 (0.49) | MMP2MMP3MEN1LMNAKMT2A | |
| SCHEMBL11838632 | 0.83 | ADRB1 (0.45) | PPARGPPARAMMP2MMP3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |