Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11837086 | 0.86 | BACE1 (0.44) | KMT2AMMP12MMP2MMP9MMP13 | |
| SCHEMBL11823054 | 0.84 | CSNK2A1 (0.53) | KMT2AMMP12MMP2MMP9MMP13 | |
| SCHEMBL11829226 | 0.83 | FOLH1 (0.41) | KMT2AMMP12MMP2MMP9MMP13 | |
| SCHEMBL11827837 | 0.83 | PPARG (0.49) | KMT2AMMP2MMP9MMP13MMP14 | |
| SCHEMBL11828303 | 0.83 | ADAMTS4 (0.41) | KMT2AMMP12MMP2MMP9MMP13 | |
| SCHEMBL11821466 | 0.83 | CD274 (0.39) | KMT2AMMP12MMP2MMP9MMP13 | |
| SCHEMBL11837826 | 0.83 | PTGS1 (0.49) | KMT2AMMP2FFAR1BACE1LMNA | |
| SCHEMBL11830550 | 0.81 | FOLH1 (0.46) | KMT2AMMP12MMP2MMP9MMP13 | |
| SCHEMBL11827162 | 0.80 | KMT2A (0.36) | KMT2AMMP12MMP2MMP9MMP13 | |
| SCHEMBL11838632 | 0.80 | ADRB1 (0.45) | KMT2AMMP12MMP2GAAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |