Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | EEF2K | O00418 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11819516 | 0.92 | ACHE (0.48) | ALDH1A1SMN1; SMN2MEN1KMT2ACYP2D6 | |
| SCHEMBL11834779 | 0.90 | HRH4 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL11830008 | 0.89 | PKM (0.48) | ALDH1A1SMN1; SMN2TSHRHDAC1HDAC6 | |
| SCHEMBL11828052 | 0.85 | LMNA (0.46) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL11834892 | 0.81 | POLB (0.53) | ALDH1A1SMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL11830966 | 0.80 | SIGMAR1 (0.44) | POLB | |
| SCHEMBL11822971 | 0.79 | POLB (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL11823392 | 0.78 | KMT2A (0.56) | ALDH1A1SMN1; SMN2MEN1KMT2ACYP2D6 | |
| SCHEMBL11827002 | 0.77 | POLB (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL11822913 | 0.73 | SIGMAR1 (0.47) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933824-A | Piperazinobutyrophenone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-01-20 | — | — | US | disclosed |