Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11826952 | 0.92 | HTR1A (0.48) | SIGMAR1CCR3HTR1ANR1I2ADRB1 | |
| SCHEMBL11828871 | 0.91 | LMNA (0.52) | SIGMAR1CCR3HTR1ADRD2KCNH2 | |
| SCHEMBL11823642 | 0.90 | SLC2A1 (0.46) | SIGMAR1CCR3HTR1ADRD2HTR2A | |
| SCHEMBL11834202 | 0.87 | DRD2 (0.61) | SIGMAR1HTR1ANR1I2ADRB1ADRA2A | |
| SCHEMBL11827418 | 0.86 | ALDH1A1 (0.54) | SIGMAR1CCR3DRD2KDM4EALDH1A1 | |
| SCHEMBL11827651 | 0.84 | HTR1A (0.51) | SIGMAR1HTR1ANR1I2ADRB1ADRA2A | |
| SCHEMBL11825896 | 0.83 | DRD2 (0.46) | SIGMAR1CCR3HTR1ADRD2SLC6A2 | |
| SCHEMBL11823392 | 0.83 | KMT2A (0.56) | ALDH1A1LMNA | |
| SCHEMBL11828423 | 0.82 | HTR1A (0.52) | SIGMAR1CCR3HTR1ANR1I2ADRB1 | |
| SCHEMBL11827870 | 0.81 | SIGMAR1 (0.58) | SIGMAR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933824-A | Piperazinobutyrophenone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-01-20 | — | — | US | disclosed |