Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 9/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11823547 | 0.80 | LMNA (0.43) | MEN1KMT2ARAB9ADHODHGAA | |
| SCHEMBL11822171 | 0.79 | KDM4E (0.43) | MEN1KMT2ARAB9ATDP1KDM4E | |
| SCHEMBL11823585 | 0.77 | GAA (0.51) | MEN1KMT2ARAB9ATDP1KDM4E | |
| SCHEMBL11823326 | 0.77 | EPHX2 (0.40) | EPHX2MEN1KMT2ARAB9ACTDSP1 | |
| SCHEMBL11825813 | 0.76 | PTGS1 (0.44) | MEN1KMT2ARAB9AEGFRMAPT | |
| SCHEMBL10817008 | 0.72 | GOT1 (0.41) | RAB9ATDP1KDM4EALDH1A1GAA | |
| SCHEMBL31231766 | 0.71 | KCNH2 (0.50) | EPHX2MEN1KMT2ARAB9ACTDSP1 | |
| SCHEMBL27197657 | 0.68 | KMT2A (0.43) | EPHX2MEN1KMT2ARAB9ACTDSP1 | |
| SCHEMBL378918 | 0.68 | CA1 (0.54) | EPHX2RAB9ATDP1ALDH1A1MAPT | |
| SCHEMBL11835366 | 0.68 | DHODH (0.40) | EPHX2MEN1KMT2ARAB9ACTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3978057-A | HYPOTENSIVE AGENTS | SANDOZ, INC. (US) | 1976-08-31 | — | — | US | disclosed |