Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Theofibrate SCHEMBL3960649 | 0.73 | ADORA2B (0.60) | LMNAMAPK1SMN1; SMN2POLBRXFP1 | |
| Theofibrate SCHEMBL49272 | 0.73 | ADORA2B (0.60) | LMNAMAPK1SMN1; SMN2POLBRXFP1 | |
| SCHEMBL11460190 | 0.72 | OPRK1 (0.55) | LMNAMAPK1SMN1; SMN2RXFP1ADORA2B | |
| SCHEMBL22288922 | 0.71 | ADORA2B (0.59) | LMNAMAPK1SMN1; SMN2POLBRXFP1 | |
| Acefylline Clofibrol SCHEMBL2110473 | 0.71 | MAPK1 (0.61) | LMNAMAPK1SMN1; SMN2POLBRXFP1 | |
| SCHEMBL10963461 | 0.70 | LMNA (0.58) | LMNAMAPK1SMN1; SMN2POLBRXFP1 | |
| SCHEMBL11328647 | 0.69 | MAPK1 (0.56) | LMNAMAPK1SMN1; SMN2POLBRXFP1 | |
| SCHEMBL27257244 | 0.68 | ADORA2B (0.58) | LMNASMN1; SMN2POLBRXFP1ADORA2B | |
| SCHEMBL20561174 | 0.66 | LMNA (1.00) | LMNAMAPK1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL11823628 | 0.65 | LMNA (0.55) | LMNAMAPK1SMN1; SMN2POLBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3984413-A | ANTILIPEMIC, ANTICHOLESTEROLEMIC; PERIPHERAL AND VASOLIDATIVE EFFECT | L. MERCKLE KG (DT) | 1976-10-05 | — | — | US | disclosed |