Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.47 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | UBE2N | P61088 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Theofibrate SCHEMBL49272 | 0.86 | ADORA2B (0.60) | LMNAMAPK1ADORA2BRXFP1ALDH1A1 | |
| Theofibrate SCHEMBL3960649 | 0.86 | ADORA2B (0.60) | LMNAMAPK1ADORA2BRXFP1ALDH1A1 | |
| Theofibrate SCHEMBL28085094 | 0.76 | LMNA (0.51) | LMNAMAPK1ADORA2BRXFP1ALDH1A1 | |
| SCHEMBL11071767 | 0.75 | OPRK1 (0.81) | OPRK1LMNAMAPK1ALDH1A1SMN1; SMN2 | |
| Acefylline Clofibrol SCHEMBL2110473 | 0.74 | MAPK1 (0.61) | LMNAMAPK1ADORA2BRXFP1SMN1; SMN2 | |
| SCHEMBL10963461 | 0.73 | LMNA (0.58) | LMNAMAPK1ADORA2BRXFP1ALDH1A1 | |
| Beclobrate SCHEMBL49779 | 0.73 | OPRK1 (1.00) | OPRK1LMNAMAPK1ALDH1A1SMN1; SMN2 | |
| Beclobrate SCHEMBL3950803 | 0.73 | OPRK1 (1.00) | OPRK1LMNAMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7141074 | 0.73 | RXFP1 (0.73) | LMNAMAPK1ADORA2BRXFP1ALDH1A1 | |
| SCHEMBL11823621 | 0.72 | LMNA (0.48) | LMNAMAPK1ADORA2BRXFP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4182902-A | P-(P'-CHLOROBENZYL) PHENOXYACETIC ACID | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1980-01-08 | — | — | US | disclosed |
| US-4153803-A | Cholesterol-lowering phenoxyalkanoic acid esters | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1979-05-08 | — | — | US | disclosed |