Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAG1 | P54619 | 2/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | FABP2 | P12104 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11824491 | 0.86 | MME (0.44) | AKR1C3AKR1C2FFAR1 | |
| SCHEMBL11827012 | 0.83 | PTGS2 (0.41) | CSNK2A1PTGS1MEN1KMT2APTGS2 | |
| SCHEMBL11825640 | 0.82 | FFAR1 (0.44) | PTGS2LMNAMAPTCYP1A2HIF1A | |
| SCHEMBL11870223 | 0.81 | PTGS1 (0.43) | PRKAG1PRKAA2PRKAB1CSNK2A1PTGS1 | |
| SCHEMBL11830155 | 0.79 | PRKAG1 (0.44) | PRKAG1PRKAA2PRKAB1CSNK2A1PTGS1 | |
| SCHEMBL11758920 | 0.79 | CSNK2A1 (0.42) | PRKAG1PRKAA2PRKAB1CSNK2A1PTGS1 | |
| SCHEMBL11824177 | 0.78 | KMO (0.39) | PTGS1PTGS2LMNATSHRAKR1C3 | |
| SCHEMBL11822909 | 0.74 | PTGDR2 (0.41) | LMNA | |
| SCHEMBL11824498 | 0.73 | CDC25A (0.37) | HPGDAKR1C3AKR1C2CYP2C19FFAR1 | |
| SCHEMBL11867114 | 0.72 | FFAR1 (0.50) | CSNK2A1PTGS1MEN1KMT2APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |