Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | ITGAL | P20701 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CRHBP | P24387 | 2/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19259524 | 0.77 | ITGB2 (0.37) | ABCG2ITGB2ICAM1ITGALLMNA | |
| SCHEMBL395819 | 0.77 | KDM4E (0.33) | ABCG2ITGB2ICAM1ITGAL | |
| SCHEMBL158578 | 0.75 | — | — | |
| SCHEMBL7003419 | 0.64 | PKM (0.42) | ABCG2ITGB2ICAM1ITGALLMNA | |
| SCHEMBL630370 | 0.62 | ABCG2 (0.31) | ABCG2ITGB2ICAM1ITGAL | |
| SCHEMBL131072 | 0.62 | ITGB2 (0.52) | ABCG2ITGB2ICAM1ITGALLMNA | |
| SCHEMBL27603346 | 0.62 | TRPA1 (0.43) | TRPA1 | |
| SCHEMBL3556 | 0.62 | — | — | |
| SCHEMBL4744946 | 0.60 | ABCG2 (0.33) | ABCG2ITGB2ICAM1ITGALLMNA | |
| SCHEMBL1420241 | 0.60 | CYP2B6 (0.42) | ABCG2ITGB2ICAM1ITGALLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1351 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044813-A1 | NOVEL SELECTIVE INHIBITORS OF LYSYL OXIDASES | PHARMAXIS LTD. (AU) | 2024-03-07 | — | — | WO | claimed |
| WO-2023146818-A2 | METHODS OF TREATING AMYLOID RELATED BRAIN DISORDERS USING NOVEL COMPOUNDS AND ANTIBODIES | T3D THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | claimed |
| CN-112142673-A | Arylalkenole derivative and preparation method and application thereof | 聊城大学 | 2020-12-29 | — | — | CN | claimed |
| EP-3548023-A1 | METHODS OF DOSE ADMINISTRATION FOR TREATING OR PREVENTING COGNITIVE IMPAIRMENT USING INDANE ACETIC ACID DERIVATIVES | T3D Therapeutics, Inc. (US) | 2019-10-09 | — | — | EP | claimed |
| WO-2019173613-A1 | SUBSTITUTED FUSED PYRROLO-DIAZEPINONES AND USES THEREOF | NORTHWESTERN UNIVERSITY (US) | 2019-09-12 | — | — | WO | claimed |
| EP-3416947-A1 | TAF1 INHIBITORS FOR THE THERAPY OF CANCER | CeMM - Forschungszentrum für Molekulare Medizin GmbH (AT) | 2018-12-26 | — | — | EP | claimed |
| WO-2018109650-A1 | SPIRO[CYCLOPENTANE-1,3'-INDOLIN]-2'-ONE DERIVATIVES AS BROMODOMAIN INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-06-21 | — | — | WO | claimed |
| WO-2018102399-A1 | METHODS OF DOSE ADMINISTRATION FOR TREATING OR PREVENTING COGNITIVE IMPAIRMENT USING INDANE ACETIC ACID DERIVATIVES | T3D THERAPEUTICS, INC. (US) | 2018-06-07 | — | — | WO | claimed |
| WO-2018102358-A1 | METHODS OF TREATING OR PREVENTING COGNITIVE IMPAIRMENT USING INDANE ACETIC ACID DERIVATIVES BASED ON APOE4 GENOTYPE | T3D THERAPEUTICS, INC. (US) | 2018-06-07 | — | — | WO | claimed |
| EP-3273964-A1 | METHODS OF TREATING LIVER DISEASE USING INDANE ACETIC ACID DERIVATIVES | T3D Therapeutics Inc. (US) | 2018-01-31 | — | — | EP | claimed |
| WO-1997030045-A1 | NOVEL BENZO-1,3-DIOXOLYL- AND BENZOFURANYL SUBSTITUTED PYRROLIDINE DERIVATIVES AS ENDOTHELIN ANTAGONISTS | ABBOTT LABORATORIES (US) | 1997-08-21 | — | — | WO | claimed |
| WO-1997030046-A1 | 4-(BENZO-1,3-DIOXOLYL)-PYRROLIDINE-3-CARBOXYLIC ACID DERIVATIVES AS ENDOTHELIN ANTAGONISTS | ABBOTT LABORATORIES (US) | 1997-08-21 | — | — | WO | claimed |
| EP-0785923-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1997-07-30 | — | — | EP | claimed |
| EP-0776324-A1 | ENDOTHELIN ANTAGONISTS | Abbott Laboratories (US) | 1997-06-04 | — | — | EP | claimed |
| WO-1996011909-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-04-25 | — | — | WO | claimed |
| WO-1996006095-A1 | ENDOTHELIN ANTAGONISTS | ABBOTT LABORATORIES (US) | 1996-02-29 | — | — | WO | claimed |
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | claimed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | claimed |
| US-4808582-A | LEARNING ENHANCEMENT | DELALANDE S.A. (FR) | 1989-02-28 | — | — | US | claimed |
| US-4636510-A | 4-phenyl-tetrahydro-furano-pyridines and anti-depressant pharmaceutical compositions containing same | BOEHRINGER INGELHEIM KG (DE) | 1987-01-13 | — | — | US | claimed |