Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29211156 | 0.80 | ALOX5 (0.48) | LMNAGAASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL28385950 | 0.79 | ALDH1A1 (0.44) | LMNAGAASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL27942078 | 0.77 | MAPT (0.59) | LMNAGAASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL28560019 | 0.77 | LMNA (0.43) | LMNAGAASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL27904667 | 0.76 | MAPT (0.41) | LMNAGAASMN1; SMN2CYP2C9ALDH1A1 | |
| SCHEMBL21457184 | 0.75 | MIF (0.59) | SMN1; SMN2CYP2C9ALDH1A1POLBL3MBTL1 | |
| SCHEMBL21457187 | 0.75 | MIF (0.59) | SMN1; SMN2CYP2C9ALDH1A1POLBL3MBTL1 | |
| SCHEMBL1119168 | 0.74 | CES2 (0.55) | LMNAGAASMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL3129239 | 0.73 | ALOX5 (0.52) | LMNASMN1; SMN2CYP3A4CYP2C9ALOX5 | |
| SCHEMBL3129250 | 0.73 | ALOX5 (0.52) | LMNASMN1; SMN2CYP3A4CYP2C9ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3998851-A | PREPARATION OF COUMARINS | UNIVERSAL OIL PRODUCTS COMPANY (US) | 1976-12-21 | — | — | US | disclosed |