Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11849955 | 0.85 | L3MBTL1 (0.50) | MAPTKMT2AMEN1HPGDL3MBTL1 | |
| SCHEMBL11825860 | 0.82 | MAT2A (0.48) | KMT2AMEN1HPGDL3MBTL1SMN1; SMN2 | |
| SCHEMBL11823985 | 0.81 | SMN1; SMN2 (0.45) | MAPTKMT2AMEN1HPGDL3MBTL1 | |
| SCHEMBL11826249 | 0.80 | HSD11B1 (0.47) | HPGDL3MBTL1SMN1; SMN2BRD4KDM4E | |
| SCHEMBL11826377 | 0.77 | PDE2A (0.47) | SMN1; SMN2BRD4ALDH1A1FNTAFNTB | |
| SCHEMBL11825891 | 0.71 | MAT2A (0.47) | L3MBTL1SMN1; SMN2BRD4LMNAFNTA | |
| SCHEMBL10842650 | 0.70 | NPSR1 (0.53) | MAPTKMT2AMEN1HPGDL3MBTL1 | |
| SCHEMBL11822266 | 0.69 | NPBWR1 (0.56) | MAPTNPBWR1KMT2AMEN1HPGD | |
| SCHEMBL11834615 | 0.69 | MAT2A (0.64) | KMT2AMEN1HPGDL3MBTL1SMN1; SMN2 | |
| SCHEMBL11702410 | 0.68 | L3MBTL1 (0.58) | MAPTKMT2AMEN1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4000153-A | TRANQUILIZERS, SEDATIVES | THE UPJOHN COMPANY (US) | 1976-12-28 | — | — | US | disclosed |
| US-4000151-A | TRANQUILIZERS, SEDATIVES | THE UPJOHN COMPANY (US) | 1976-12-28 | — | — | US | disclosed |