Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 10/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11827920 | 0.82 | PTGS2 (0.49) | AKR1C2PTGS1PTGS2ALOX5LMNA | |
| SCHEMBL11829349 | 0.81 | ATM (0.40) | P2RX3ATML3MBTL1AKR1C2AKR1C1 | |
| SCHEMBL11823310 | 0.79 | P2RX3 (0.41) | P2RX3AKR1C2AKR1C1PTGS1PTGS2 | |
| SCHEMBL11836371 | 0.78 | CSNK2A1 (0.46) | ADRB3 | |
| SCHEMBL11831274 | 0.77 | GABRA1 (0.39) | P2RX3AKR1C2AKR1C1KMO | |
| SCHEMBL11829438 | 0.76 | P2RX3 (0.37) | P2RX3AKR1C2AKR1C1 | |
| SCHEMBL11825474 | 0.74 | PTGDR2 (0.38) | P2RX3 | |
| SCHEMBL7307992 | 0.72 | ACE (0.47) | PTGS1ALOX5TSHR | |
| SCHEMBL7307985 | 0.72 | ACE (0.47) | PTGS1ALOX5TSHR | |
| SCHEMBL6545539 | 0.72 | HTT (0.50) | L3MBTL1RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |