Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | DRD5 | P21918 | 2/20 | 0.47 |
| ▸ | HRH2 | P25021 | 2/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11823392 | 0.91 | KMT2A (0.56) | MEN1KMT2ATSHRHTR7GFER | |
| SCHEMBL11830955 | 0.89 | POLB (0.46) | KMT2ATSHRCACNA1FDRD4DRD5 | |
| SCHEMBL11826952 | 0.86 | HTR1A (0.48) | HTR2AHRH1SLC6A3HTR2CSIGMAR1 | |
| SCHEMBL11828042 | 0.85 | GFER (0.55) | MEN1KMT2AGFERTACR1MC4R | |
| SCHEMBL11819506 | 0.83 | KMT2A (0.56) | MEN1KMT2ATSHRDRD4HTR7 | |
| SCHEMBL11834886 | 0.81 | GFER (0.54) | MEN1KMT2ATSHRGFERTACR1 | |
| SCHEMBL11829997 | 0.80 | PKM (0.48) | KMT2ATSHRTACR1GAAPTGDR2 | |
| SCHEMBL11834779 | 0.80 | HRH4 (0.47) | MEN1KMT2ACACNA1FDRD4DRD5 | |
| SCHEMBL11822960 | 0.79 | TACR1 (0.69) | MEN1KMT2ATACR1L3MBTL1 | |
| SCHEMBL11822913 | 0.79 | SIGMAR1 (0.47) | HTR2AHRH1SLC6A3HTR2CSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933824-A | Piperazinobutyrophenone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-01-20 | — | — | US | disclosed |