Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | TACR1 | P25103 | 5/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11823392 | 0.92 | KMT2A (0.56) | KMT2AMEN1TACR1ALDH1A1L3MBTL1 | |
| SCHEMBL11826994 | 0.86 | TACR1 (0.61) | KMT2AMEN1TACR1DRD2DRD4 | |
| SCHEMBL11834769 | 0.83 | MEN1 (0.50) | KMT2AMEN1TACR1DRD4DRD3 | |
| SCHEMBL11828871 | 0.83 | LMNA (0.52) | DRD2DRD4DRD3ACHELMNA | |
| SCHEMBL11829997 | 0.81 | PKM (0.48) | KMT2ATACR1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL11819516 | 0.78 | ACHE (0.48) | KMT2AMEN1DRD2DRD4DRD3 | |
| SCHEMBL11828042 | 0.78 | GFER (0.55) | KMT2AMEN1TACR1LMNA | |
| SCHEMBL15229645 | 0.76 | APEX1 (0.59) | KMT2AMEN1ALDH1A1L3MBTL1HTR7 | |
| SCHEMBL11822913 | 0.75 | SIGMAR1 (0.47) | DRD2ALDH1A1LMNA | |
| SCHEMBL11822960 | 0.74 | TACR1 (0.69) | KMT2AMEN1TACR1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933824-A | Piperazinobutyrophenone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-01-20 | — | — | US | disclosed |