Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.44 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 5/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11833610 | 0.85 | CSNK2A1 (0.50) | PPARAPPARGMEN1KMT2A | |
| SCHEMBL11837755 | 0.83 | ALDH1A1 (0.43) | MMETRPA1PPARAPPARGKMT2A | |
| SCHEMBL11830972 | 0.83 | MME (0.50) | MMEMAOBITGB1ITGA4ITGB7 | |
| SCHEMBL11830999 | 0.82 | PPARG (0.51) | MMEPPARAPPARG | |
| SCHEMBL14946403 | 0.80 | TRPA1 (0.63) | TRPA1MEN1CYP2C19KMT2AHSD17B10 | |
| SCHEMBL8289807 | 0.80 | TRPA1 (0.63) | TRPA1MEN1CYP2C19KMT2AHSD17B10 | |
| SCHEMBL11831724 | 0.79 | ADAMTS4 (0.52) | TRPA1PPARAPPARGMEN1KMT2A | |
| SCHEMBL4959048 | 0.78 | ALOX15 (0.63) | MMEMAOBCYP2A6MEN1ALOX15 | |
| SCHEMBL31398344 | 0.78 | ALOX15 (0.63) | MMEMAOBCYP2A6MEN1ALOX15 | |
| SCHEMBL11824499 | 0.77 | MME (0.62) | MMEMAOBCYP2A6TRPA1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |