Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | MME | P08473 | 7/20 | 0.40 |
| ▸ | ACE | P12821 | 7/20 | 0.40 |
| ▸ | CPA1 | P15085 | 4/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.38 |
| ▸ | PSAT1 | Q9Y617 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11835452 | 0.85 | CD274 (0.43) | TRPA1PPARAPPARGMMEACE | |
| SCHEMBL11827701 | 0.83 | MME (0.50) | TRPA1PPARAPPARGMMEKMT2A | |
| SCHEMBL11830736 | 0.83 | ALDH1A1 (0.43) | ALDH1A1MAPK1PPARAPPARGMME | |
| SCHEMBL11825730 | 0.81 | MME (0.47) | TRPA1PPARAPPARGMMEACE | |
| SCHEMBL8289807 | 0.80 | TRPA1 (0.63) | TRPA1ACECPA1KMT2ASRR | |
| SCHEMBL14946403 | 0.80 | TRPA1 (0.63) | TRPA1ACECPA1KMT2ASRR | |
| SCHEMBL11831724 | 0.79 | ADAMTS4 (0.52) | ALDH1A1TRPA1PPARAPPARGCPA1 | |
| SCHEMBL11830999 | 0.76 | PPARG (0.51) | PPARAPPARGMMEACECPA1 | |
| SCHEMBL11829462 | 0.74 | MMP12 (0.47) | ALDH1A1MAPK1PPARAMMEACE | |
| SCHEMBL11833610 | 0.74 | CSNK2A1 (0.50) | PPARAPPARGKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |