Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11836851 | 0.86 | ALOX5 (0.42) | HPGDALDH1A1CYP2D6KDM4ETP53 | |
| SCHEMBL11830155 | 0.84 | PRKAG1 (0.44) | HPGDALDH1A1CYP2D6KDM4ETP53 | |
| SCHEMBL11826969 | 0.83 | AKR1C3 (0.44) | HPGDALDH1A1CYP2D6KDM4ETP53 | |
| SCHEMBL11825726 | 0.83 | ALDH1A1 (0.38) | HPGDALDH1A1CYP2D6KDM4ETP53 | |
| SCHEMBL11831306 | 0.83 | AKR1C3 (0.56) | HPGDPTGS1MEN1PTGS2KMT2A | |
| SCHEMBL11829271 | 0.83 | ADAMTS4 (0.38) | HPGDALDH1A1CYP2D6KDM4ETP53 | |
| SCHEMBL11826110 | 0.83 | HPGD (0.38) | HPGDALDH1A1CYP2D6KDM4ETP53 | |
| SCHEMBL11827335 | 0.83 | AKR1C3 (0.47) | AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL11836380 | 0.81 | PTGS1 (0.38) | HPGDALDH1A1CYP2D6KDM4ETP53 | |
| SCHEMBL11830219 | 0.80 | FFAR1 (0.39) | HPGDALDH1A1CYP2D6KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |